How optical/biophysical complements biochemical characterizations in cellular mechanobiology

Yi-Chun Chen, M. H. Yang, A. Chiou*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


In recent years, the critical roles of physical & mechanical cell-cell interactions and cell-ECM (extra-cellular matrix) interactions in the physiological functions and the pathological status at the cellular level have received increasing attentions [1, 2]. Specifically, the studies of the cellular response to external physical, mechanical, and chemical stimuli in the context of Epithelial-Mesenchymal Transition (EMT) and the associated reversed process of Mesenchymal-Epithelial Transition (MET), which play an essential role in developmental biology, and in cancer metastasis as well as in stem cell differentiation [2-4], have shed light on the molecular pathways and/or mechanisms of these processes with important biomedical implications.
Original languageEnglish
Title of host publicationJSAP-OSA Joint Symposia, JSAP 2015
PublisherOSA - The Optical Society
ISBN (Electronic)9781557528209
StatePublished - Sep 2015
EventJSAP-OSA Joint Symposia, JSAP 2015 - Nagoya, Japan
Duration: 13 Sep 201516 Sep 2015

Publication series

NameOptics InfoBase Conference Papers
VolumePart F132-JSAP 2015


ConferenceJSAP-OSA Joint Symposia, JSAP 2015

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