High power NIR fiber-optic femtosecond Cherenkov radiation and its application on nonlinear light microscopy

Ming-Che Chan, Chi Hsiang Lien, Jyan Yo Lu, Bo Han Lyu

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

We reported a record high power (>250 mW) and compact nearinfrared fiber-optic femtosecond Cherenkov radiation source and its new application on nonlinear light microscopy for the first time (to our best knowledge). The high power femtosecond Cherenkov radiation was generated by 1.03 μm femtosecond pulses from a portable diode-pumped laser and a photonic crystal fiber as a compact, flexible, and highly efficient wavelength convertor. Sectioned nonlinear light microscopy images from mouse brain blood vessel network and rat tail tendon were then performed by the demonstrated light source. Due to the advantages of its high average output power (>250 mW), high pulse energy (>4 nJ), excellent wavelength conversion efficiency (>40%), compactness, simplicity in configuration, and turn-key operation, the demonstrated femtosecond Cherenkov radiation source could thus be widely applicable as an alternative excitation source to mode-locked Ti:Sapphire lasers for future clinical nonlinear microscopy or other applications requiring synchronized multi-wavelength light sources.

Original languageEnglish
Pages (from-to)9498-9507
Number of pages10
JournalOptics Express
Volume22
Issue number8
DOIs
StatePublished - 21 Apr 2014

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