Grafting of 18-crown-6 functionalization on microcantilever biosensor for Pb2+ poisoning detection

Yen I. Chou*, Chi-Chuan Wang, Cheng Yen Wu, Wei Sun Tseng, Kai Sheng Hsu, Shih Ming Lai

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Microcantilevers with surface functionalizations recently have provided the possibilities, of chemimechnanical transductions for sensing applications. In this study, the 18-crown-6 was grafted onto the carboxyl-microcantilever as surface functionalization for Pb2+ detection. Microcantilever with 18-crown-6 functionalization exhibited the surface configurations of adequate wetting property, strong covalent immobilization and selective Pb2+ adsorption. Experimental results revealed that the 18-crown-6 functionalized microcantilever exhibited the excellent Pb2+ sensing performances with a high sensitivity of 42.1 nm/log[Pb2+], a low detection limit as well as a wide detectable regime ranging from 10-7 to 10-61 M.

Original languageEnglish
Pages (from-to)840-843
Number of pages4
JournalSensor Letters
Volume6
Issue number6
DOIs
StatePublished - 1 Dec 2008

Keywords

  • 18-crown-6
  • Microcantilever
  • Pb poisoning detection

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