Gold nanorods in photodynamic therapy, as hyperthermia agents, and in near-infrared optical imaging

Wen Shuo Kuo*, Chich Neng Chang, Yi Ting Chang, Meng Heng Yang, Yi Hsin Chien, Shean-Jen Chen, Chen Sheng Yeh

*Corresponding author for this work

Research output: Contribution to journalArticle

257 Scopus citations

Abstract

(Figure Presented) The best of three worlds: Cold nanorods coated with poly(styrene-alt-maleic acid) (see picture; pink), the photosensitizer indocyanine green (black), and antibodies (green "Y") serve not only as photodynamic therapy and hyperthermia agents to destroy malignant cells, but they also act as optical contrast agents to simultaneously to monitor cells by imaging in the near-IR region.

Original languageEnglish
Pages (from-to)2711-2715
Number of pages5
JournalAngewandte Chemie - International Edition
Volume49
Issue number15
DOIs
StatePublished - 1 Apr 2010

Keywords

  • Gold
  • Hyperthermia
  • Imaging agents
  • Nanostructures
  • Photodynamic therapy

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