Genome-wide alternative splicing events detection through analysis of large scale ESTs

F. R. Hsu, Hwan You Chang, Yaw Lin Lin, Yin Te Tsai, Hwei-Ling Peng, Ying Tsong Chen, Che Feng Chen, Chia Yang Cheng, Chia Hung Liu, Min Yao Shih

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

In the past several years, the analysis of alternative splicing and its application to identify the origins of disease has been gaming momentum. Therefore, we developed a value added transcriptome database (Avatar). We maped EST (expressed sequence tag) and mRNA sequences onto whole human genomic sequence. We identified 9,937 alternative splicing relationships genes through an analysis of large-scale ESTs. Besides, we provided alternative splicing information for six organisms: Homo sapiens, Mus musculus, Rattus norvegicus, Caenorhabditis elegans, Drosophila melanogaster and Arabidopsis thaliana.

Original languageEnglish
Title of host publicationProceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004
Pages310-316
Number of pages7
DOIs
StatePublished - 24 Sep 2004
EventProceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004 - Taichung, Taiwan
Duration: 19 May 200421 May 2004

Publication series

NameProceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004

Conference

ConferenceProceedings - Fourth IEEE Symposium on Bioinformatics and Bioengineering, BIBE 2004
CountryTaiwan
CityTaichung
Period19/05/0421/05/04

Keywords

  • Alternative splicing
  • EST

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