Flow network tracking for spatiotemporal and periodic point matching: Applied to cardiac motion analysis

Nripesh Parajuli*, Allen Lu, Kevinminh Ta, John Stendahl, Nabil Boutagy, Imran Alkhalil, Melissa Eberle, Geng Shi Jeng, Maria Zontak, Matthew O'Donnell, Albert J. Sinusas, James S. Duncan

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The accurate quantification of left ventricular (LV) deformation/strain shows significant promise for quantitatively assessing cardiac function for use in diagnosis and therapy planning. However, accurate estimation of the displacement of myocardial tissue and hence LV strain has been challenging due to a variety of issues, including those related to deriving tracking tokens from images and following tissue locations over the entire cardiac cycle. In this work, we propose a point matching scheme where correspondences are modeled as flow through a graphical network. Myocardial surface points are set up as nodes in the network and edges define neighborhood relationships temporally. The novelty lies in the constraints that are imposed on the matching scheme, which render the correspondences one-to-one through the entire cardiac cycle, and not just two consecutive frames. The constraints also encourage motion to be cyclic, which an important characteristic of LV motion. We validate our method by applying it to the estimation of quantitative LV displacement and strain estimation using 8 synthetic and 8 open-chested canine 4D echocardiographic image sequences, the latter with sonomicrometric crystals implanted on the LV wall. We were able to achieve excellent tracking accuracy on the synthetic dataset and observed a good correlation with crystal-based strains on the in-vivo data.

Original languageEnglish
Pages (from-to)116-135
Number of pages20
JournalMedical Image Analysis
Volume55
DOIs
StatePublished - Jul 2019

Keywords

  • Echocardiography
  • Flow network
  • Motion
  • Neural networks

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    Parajuli, N., Lu, A., Ta, K., Stendahl, J., Boutagy, N., Alkhalil, I., Eberle, M., Jeng, G. S., Zontak, M., O'Donnell, M., Sinusas, A. J., & Duncan, J. S. (2019). Flow network tracking for spatiotemporal and periodic point matching: Applied to cardiac motion analysis. Medical Image Analysis, 55, 116-135. https://doi.org/10.1016/j.media.2019.04.007