This study experimentally investigates the film condensation of R-22 and R-410A on two horizontal enhanced tubes. The test tubes include a GEWA-C and a GEWA-TWX. Data was measured at three different saturation temperatures (35 °C, 40 °C and 45 °C) in accordance with the range of practical condensation conditions in the air-conditioning and refrigeration applications. Average heat transfer coefficients were determined by overall heat transfer coefficients based on energy balance. The comparisons of heat transfer coefficients between R-22 and R-410A for both test tubes were presented.