Fabrication of a flexible and disposable microreactor using a dry film photoresist

Yuan Chien Tsai, Shung Jim Yang, Hsun Tsing Lee, Hsiu Ping Jen, You-Zung Hsieh*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


In this paper, we demonstrate that a low-cost flexible microreactor can be manufactured using a dry film photoresist in conjunction with photolithographic and hot roll lamination techniques. A microfluidic flow path and sample reservoir patterns were prefabricated in a dry film photoresist tape using traditional photolithographic methods. This tape was sandwiched between two plastic films - wells were prepouched on the cover film - that were bonded upon passage through a hot roll laminator. A simple Plexiglas reactor holder was designed and constructed to use in evaluating the flexible microchip reactor. We demonstrate a chemical synthesis of polyaniline that was performed with this polymeric microreactor using a hydrodynamic flow control system. The fabrication of this microreactor suggests that there is great potential for designing and prototyping disposable microscale reaction systems using dry film photoresist for a range of chemical and biochemical syntheses.

Original languageEnglish
Pages (from-to)683-688
Number of pages6
JournalJournal of the Chinese Chemical Society
Issue number3
StatePublished - 1 Jan 2006


  • Dry film photoresist
  • Microfluidic devices
  • Microreactor

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