Experimental investigation of bulk response of cells on optoelectronic dielectrophoresis chip

Srinivasu Valagerahally Puttaswamy*, Shih Mo Yang, Shilpa Sivashankar, Kuo Wei Chang, Long Hsu, Cheng Hsien Liu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The mechanism of the particle interactions is still inconclusive, even though many researchers have tried to figure out the particle-particle interactions under the influence of electric field. In this paper we report an experimental investigation of electrostatic attraction and repulsion of endothelial cells in an image-driven light induced dielectrophoresis (DEP) apparatus. The optoelectronic tweezers (OET) device consists of a planar structure having one or more portions which are photoconductive to convert incoming light to a change in the electric field pattern. When the cells are manipulated in OET chip at a frequency near the threshold of electrolysis, cells exhibits numerous interesting phenomena such as spinning, collision, rotation and pearl chain effect in three-dimensional (3D) space. All of these cell behaviors at such critical frequencies on this OET chip are reported.

Original languageEnglish
Title of host publication2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012
Pages162-165
Number of pages4
DOIs
StatePublished - 1 Jun 2012
Event7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012 - Kyoto, Japan
Duration: 5 Mar 20128 Mar 2012

Publication series

Name2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012

Conference

Conference7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012
CountryJapan
CityKyoto
Period5/03/128/03/12

Keywords

  • cell behavior
  • Dielectrophoresis
  • optoelectronic tweezers
  • pearl chain effect

Fingerprint Dive into the research topics of 'Experimental investigation of bulk response of cells on optoelectronic dielectrophoresis chip'. Together they form a unique fingerprint.

Cite this