Evanescent planar wave system for reading DNA microarrays on thin glass slides

Pei Kuen Wei*, Peng Cheng Huang, Yi-Chun Chen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

A new optical reading system that can read the fluorescent signals of microarrays on glass slides with large detection area and high sensitivity is proposed. This system uses gratings (1200 g/mm) with several micron thick PDMS film on surface. Normally incident laser was coupled into a thin glass slide by grating coupling and confined in the slide due to the total internal reflection (TIR). The TIR generates evanescent planar wave on the glass surface. The evanescent wave was employed to excite the fluorescent signals in the microarrays. The method takes the advantages of low excitation background, large and uniform detection area.

Original languageEnglish
Title of host publicationSecond Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004
Pages236-237
Number of pages2
DOIs
StatePublished - 1 Dec 2004
EventSecond Asian and Pacific Rim Symposium on Biophotonics, APBP 2004 - Taipei, Taiwan
Duration: 15 Dec 200417 Dec 2004

Publication series

NameSecond Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004

Conference

ConferenceSecond Asian and Pacific Rim Symposium on Biophotonics, APBP 2004
CountryTaiwan
CityTaipei
Period15/12/0417/12/04

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    Wei, P. K., Huang, P. C., & Chen, Y-C. (2004). Evanescent planar wave system for reading DNA microarrays on thin glass slides. In Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004 (pp. 236-237). (Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004). https://doi.org/10.1109/APBP.2004.1412369