Evaluation of cell impedance using a μ-channel

Chia-Hung Tsai*, Makoto Kaneko, Fumihito Arai

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

We propose a novel approach for evaluating both the stiffness and internal viscosity of a cell by using a μ-channel. The key idea comes from the fact that cell behavior in the channel can be separated into two phases; one is in the entrance area where the cell heavily deforms within a short distance, and the other is in the remaining area where the cell keeps almost constant shape. By focusing on the cell behavior in the first area, we can evaluate the internal viscosity of a cell. By focusing on the cell behavior in the second area, we can evaluate the stiffness. We conducted experiments with two different initial velocities of red blood cells, and discussed the results from the viewpoint of applicability.

Original languageEnglish
Title of host publication2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
Pages5518-5521
Number of pages4
DOIs
StatePublished - 14 Dec 2012
Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
Duration: 28 Aug 20121 Sep 2012

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Conference

Conference34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
CountryUnited States
CitySan Diego, CA
Period28/08/121/09/12

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  • Cite this

    Tsai, C-H., Kaneko, M., & Arai, F. (2012). Evaluation of cell impedance using a μ-channel. In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012 (pp. 5518-5521). [6347244] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/EMBC.2012.6347244