ESI MS for Microsized Bioparticles

Abdil Ozdemir, Jung Lee Lin, Mustafa Gulfen, Szu Hsueh Lai, Chun Jen Hsiao, G. Chen, Chung Hsuan Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


An ESI ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large bioparticles. Mass calibration of the instrument was performed using commercially available polystyrene (PS) microparticles with a size comparable to cancer cells. Different sizes of MCF-7 breast cancer cells (8 to 15 μm) were used in this study. The masses of different cancer cells were measured. This system allows for the analysis of all types of particles.

Original languageEnglish
Pages (from-to)13195-13202
Number of pages8
JournalAnalytical Chemistry
Issue number24
StatePublished - 19 Dec 2017

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