The progress of the electronics has been conducted until today by the downsizing of devices for more than 100 year since its beginning in early 20th century. However, it is believed now that the downsizing will reach its limit in several years because of several sure reasons. After reaching the limit, we cannot expect such a big progress as the past for electron devices in terms of cost, performance and energy consumption. Then, the effort will be focused to develop various kind of electron devices such as new memory, sensors, power, photovoltaic, battery and MEMS devices which are demanded for IoT era. In a long term, our research and development will shift to how to use the existing bio system more efficiently rather than developing only solid-state devices only.