Dynamic regulation on energy landscape evolution of single-molecule protein by conformational fluctuation

Chien Y. Lin*, Jung Y. Huang, Leu Wei Lo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We formalize a theory to help explore the effect of conformational fluctuation on the energy landscape evolution of single-molecule protein. Using this formalization, we investigate the photon emission from single photoactivated fluorescent protein. A bimodal regulation on the energy landscape evolution was discovered, and its origin was attributed to slow conformational fluctuations of the protein matrix.

Original languageEnglish
Article number021925
JournalPhysical Review E - Statistical, Nonlinear, and Soft Matter Physics
Volume86
Issue number2
DOIs
StatePublished - 31 Aug 2012

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