Diffuse optical multipatch technique for tissue oxygenation monitoring: Clinical study in intensive care unit

Chun Yang Wang*, Ming Lung Chuang, Shinn Jye Liang, Jui Che Tsai, Ching-Cheng Chuang, Yao Sheng Hsieh, Chih Wei Lu, Po Lei Lee, Chia-Wei Sun

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Diffuse optical multipatch technique is used to assess spatial variations in absorption and scattering in biological tissue, by monitoring changes in the concentration of oxyhemoglobin and deoxyhemoglobin. In our preliminary study, the temporal tracings of tissue oxygenation are measured using diffuse optical multipatch measurement and a venous occlusion test, employing normal subjects and ICU patients suffering from sepsis and heart failure. In experiments, obvious differences in tissue oxygenation signals were observed among all three groups. This paper discusses the physiological relevance of tissue oxygenation with respect to disease.

Original languageEnglish
Article number5756457
Pages (from-to)87-94
Number of pages8
JournalIEEE Transactions on Biomedical Engineering
Volume59
Issue number1
DOIs
StatePublished - 1 Jan 2012

Keywords

  • Diffuse optical multipatch technique
  • diffuse optical spectroscopic imaging (DOSI)
  • heart failure
  • intensive care medicine
  • near-infrared spectroscopy (NIRS)
  • oxygenation dynamics
  • sepsis
  • venous occlusion test (VOT)

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