Development of brain focal cooling measurement for induced epilepsy

Kuan Chou Hou*, Chih Wei Chang, Chun Ying Lin, Jin-Chern Chiou, Yu Hsing Huang, Fu Zen Shaw

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cooling is a potential treatment for induced epilepsy. There is no electric current pass through the organization of brain because it will damage it with high temperature. EEG electrodes and thermal electric (TE) coolers were integrated and placed in the head of rat. EEG electrodes were used to measure brain waveform and TE cooler was employed to be a cooling actuator to decrease temperature on the surface of cortex. Brain cortex can be cooled down lower than body temperature in order to suppress epilepsy and variance of temperature do not exceed over ± 2 °C. The experiment for suppressing epilepsy was implemented and brain waveforms of induced epilepsy were detected. Suppression with focal cooling is the main technology for the current study. We are currently determining the efficacy for the therapy of certain focal epilepsies.

Original languageEnglish
Title of host publicationNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
Pages603-606
Number of pages4
DOIs
StatePublished - 4 Oct 2011
Event6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan
Duration: 20 Feb 201123 Feb 2011

Publication series

NameNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Conference

Conference6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
CountryTaiwan
CityKaohsiung
Period20/02/1123/02/11

Keywords

  • Epilepsy
  • MEMS
  • Rat
  • TE cooler

Fingerprint Dive into the research topics of 'Development of brain focal cooling measurement for induced epilepsy'. Together they form a unique fingerprint.

  • Cite this

    Hou, K. C., Chang, C. W., Lin, C. Y., Chiou, J-C., Huang, Y. H., & Shaw, F. Z. (2011). Development of brain focal cooling measurement for induced epilepsy. In NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (pp. 603-606). [6017427] (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems). https://doi.org/10.1109/NEMS.2011.6017427