The present study outlines the design of a magnetohydrodynamic (MHD) thruster system which is capable to power a 3-meter ship model cruising at a speed of V =0.5m/s using the Lorentz force generated by the electric field and magnetic field in conducting seawater. Based on the computational fluid dynamics (CFD) simulation of a modified Delft 372 catamaran model, the thrust needed to achieve the targeted cruising speed is first estimated. To achieve the estim- ated magnitude of the thrust, dimensions of thruster modules are designed based on numerical simulations of magnetic field, for better distributions of the strength and uniformity of the mag- netic field. Additional CFD simulations of the flows through the thruster module, coupled with magnetic and electric fields, are conducted to realize the hydrodynamics. Consequently, several configurations of thruster modules are manufactured and experimented. A particular config- uration of a shielded two-unit module is chosen to power the ship model. Finally, a complete system of MHD-1 marine vehicle, including a ship model, multiple MHD thruster modules and power suppliers, is assembled and tested. The system is shown capable to cruise closely to the targeted speed.