Over the last few decades, there has been a growing interest in technology assisted multimedia learning. The purpose of this study was to develop an online multimedia learning system, TEDQuiz, for English language learners to practice their listening skills. The system is comprised of an easy-to-use browser extension and a personalized online learning management platform. This can help learners to manage listening materials by automatically generating multiple-choice questions, synchronously connecting to friends in a social network website and personally managing their learning progress and word bank. The use of the system involves six steps: skimming, asking questions, listening, answering questions, linking and reviewing. Taking TED talks as an example, users can skim the website, have guiding questions, listen to talks, answer the questions, link to a social network website, and review their profile on the TEDQuiz website. The experimental results demonstrate that students with the TEDQuiz system spent more time on video watching. In the questionnaire, students had a positive view of the functions of the TEDQuiz system. They thought it is useful and helpful, and they were willing to use it in the future. We also found that the usefulness factor was statistically significant in predicting the future usage of TEDQuiz.