Design and synthesis of combinatorial scaffolds-diazepinone and homopiperazine

Chung-Ming Sun*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A general method for the construction of diazepinone and homopiperazine scaffolds has been developed by utilizing Beckmann rearrangement as the key step in the design. Using this methodology, the synthesis of a diverse diazepinone library with three points of diversity has been achieved starting from readily available 4-piperidone.

Original languageEnglish
Pages (from-to)48-50
Number of pages3
JournalLetters in Drug Design and Discovery
Issue number1
StatePublished - 1 Feb 2005

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