Cost-sensitive classification on pathogen species of bacterial meningitis by surface enhanced Raman scattering

Te Kang Jan*, Hsuan Tien Lin, Hsin Pai Chen, Tsung Chen Chern, Chung Yueh Huang, Bing Cheng Wen, Chia Wen Chung, Yung Jui Li, Ya Ching Chuang, Li Li Li, Yu Jiun Chan, Juen Kai Wang, Yuh Lin Wang, Chi Hung Lin, Da Wei Wang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

We propose a pathogen-classification system using the Surface-Enhanced Raman Scattering (SERS) platform. The system differentiates the pathogens based on their SERS spectra, which are believed to be related to the surface chemical components. The specialty of the system is to not only consider the usual classification accuracy, but also pay attention to the different types of costs during misclassification. For instance, due to the effectiveness of treatments, the cost of classifying a Gram-positive bacterium as another Gram-positive one should be lower than the cost of classifying a Gram-positive bacterium as a Gram-negative one. We express the task as the cost-sensitiveclassification problem, and take state-of-the-art cost-sensitiveclassification algorithms from the machine learning community to conquer the task. Our experimental study validates the usefulness of those algorithms on building the system.

Original languageEnglish
Title of host publicationProceedings - 2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011
Pages390-393
Number of pages4
DOIs
StatePublished - 2011
Event2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011 - Atlanta, GA, United States
Duration: 12 Nov 201115 Nov 2011

Publication series

NameProceedings - 2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011

Conference

Conference2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011
CountryUnited States
CityAtlanta, GA
Period12/11/1115/11/11

Keywords

  • Cost-sensitive Classification
  • SERS
  • SVM

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    Jan, T. K., Lin, H. T., Chen, H. P., Chern, T. C., Huang, C. Y., Wen, B. C., Chung, C. W., Li, Y. J., Chuang, Y. C., Li, L. L., Chan, Y. J., Wang, J. K., Wang, Y. L., Lin, C. H., & Wang, D. W. (2011). Cost-sensitive classification on pathogen species of bacterial meningitis by surface enhanced Raman scattering. In Proceedings - 2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011 (pp. 390-393). [6120471] (Proceedings - 2011 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2011). https://doi.org/10.1109/BIBM.2011.133