Catch, load and launch toward on-chip active cell evaluation

Ryo Murakami, Chia-Hung Tsai*, Hiroaki Ito, Motomu Tanaka, Shinya Sakuma, Fumihito Arai, Makoto Kaneko

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations

Abstract

An automatic system for evaluating single cell viscoelasticity is proposed and tested in this paper. The system includes three main operations, and they are the operations of catch, load and launch. In the catch operation, the system is capable of capturing a target cell by high-speed vision and high-frequency flow control. The captured cell is pushed into a narrow constriction for the load operation. Different durations of loading time are applied to cells for evaluating cell viscoelasticity. Finally, the cell is launched out from the constriction, and the recovery response of the cell is monitored for cell characterization. Human red blood cells are experimentally tested by the proposed system. The experimental results show that the system successfully perform the evaluation, and the viscoelastic characteristics of the cells are discussed.

Original languageEnglish
Title of host publication2016 IEEE International Conference on Robotics and Automation, ICRA 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1713-1718
Number of pages6
ISBN (Electronic)9781467380263
DOIs
StatePublished - 8 Jun 2016
Event2016 IEEE International Conference on Robotics and Automation, ICRA 2016 - Stockholm, Sweden
Duration: 16 May 201621 May 2016

Publication series

NameProceedings - IEEE International Conference on Robotics and Automation
Volume2016-June
ISSN (Print)1050-4729

Conference

Conference2016 IEEE International Conference on Robotics and Automation, ICRA 2016
CountrySweden
CityStockholm
Period16/05/1621/05/16

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