Catalytic behaviors in modulating enzymatic activity through different-sized gold nanoparticles

Chung Shu Wu, Chia Tien Wu, Chieh Chen, Chung Chih Huang, Yu Lin Yeh, Yuh-Shyong Yang, Fu-Hsiang Ko*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have demonstrated that gold nanoparticles (AuNPs) can effectively associate with enzyme through spontaneous adsorption to afford supramolecular complexes, resulting in a significant increase of its enzymatic activity. In this work, we embarked on a study of the interactions between the different-sized AuNPs and the substrate through quantifying the kinetic parameters (Kcat and KM). The diversity of size allows us to probe the role of catalytic behaviors in modulating enzymatic activity.

Original languageEnglish
Title of host publicationINEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings
Pages334-335
Number of pages2
DOIs
StatePublished - 5 May 2010
Event2010 3rd International Nanoelectronics Conference, INEC 2010 - Hongkong, China
Duration: 3 Jan 20108 Jan 2010

Publication series

NameINEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings

Conference

Conference2010 3rd International Nanoelectronics Conference, INEC 2010
CountryChina
CityHongkong
Period3/01/108/01/10

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  • Cite this

    Wu, C. S., Wu, C. T., Chen, C., Huang, C. C., Yeh, Y. L., Yang, Y-S., & Ko, F-H. (2010). Catalytic behaviors in modulating enzymatic activity through different-sized gold nanoparticles. In INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings (pp. 334-335). [5424727] (INEC 2010 - 2010 3rd International Nanoelectronics Conference, Proceedings). https://doi.org/10.1109/INEC.2010.5424727