Cascade carbonylation methods leading to β-diketones and β-functionalized δ-diketones

Katsukiyo Miura; Mami Tojino; Naoki Fujisawa; Akira Hosomi; Ilhyong Ryu

doi:10.1002/anie.200453702

Cascade carbonylation methods leading to β-diketones and β-functionalized δ-diketones

Katsukiyo Miura, Mami Tojino, Naoki Fujisawa, Akira Hosomi^*, Ilhyong Ryu

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A radical combination: An intermolecular cascade reaction involving alkyl halides, CO, electron-deficient alkenes, and stannyl enolates proceeds smoothly by a radical chain pathway to give four-component coupling products in good to high yields (see scheme). A series of 1,5-diketones with a substituent at the 3-position was prepared by this method.

Original language	English
Pages (from-to)	2423-2425
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	43
Issue number	18
DOIs	https://doi.org/10.1002/anie.200453702
State	Published - 26 Apr 2004

Keywords

Carbonylation
Enolates
Ketones
Multicomponent reactions
Tin

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AU - Fujisawa, Naoki

AU - Hosomi, Akira

AU - Ryu, Ilhyong

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KW - Carbonylation

KW - Enolates

KW - Ketones

KW - Multicomponent reactions

KW - Tin

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Cascade carbonylation methods leading to β-diketones and β-functionalized δ-diketones

Abstract

Keywords

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