Carbon-based materials for photo-triggered theranostic applications

Karunya Albert, Hsin-Yun Hsu*

*Corresponding author for this work

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Carbon-based nanomaterials serve as a type of smart material for photo-triggered disease theranostics. The inherent physicochemical properties of these nanomaterials facilitate their use for less invasive treatments. This review summarizes the properties and applications of materials including fullerene, nanotubes, nanohorns, nanodots and nanographenes for photodynamic nanomedicine in cancer and antimicrobial therapies. Carbon nanomaterials themselves do not usually act as photodynamic therapy (PDT) agents owing to the high hydrophobicity, however, when the surface is passivated or functionalized, these materials become great vehicles for PDT. Moreover, conjugation of carbonaceous nanomaterials with the photosensitizer (PS) and relevant targeting ligands enhances properties such as selectivity, stability, and high quantum yield, making them readily available for versatile biomedical applications.

Original languageEnglish
Article number1585
JournalMolecules
Volume21
Issue number11
DOIs
StatePublished - 1 Nov 2016

Keywords

  • Carbon materials
  • Nanomedicine
  • Near infrared-triggered agents
  • Photodynamic therapy
  • Photosensitizer

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