Building the long, periodic ssDNA nanotemplate from tumor marker recognition for nanodevice

Ming Yu Lin*, Fu Han Ho, Chung Yao Yang, Jiann Shiun Kao, J. Andrew Yeh, Yuh-Shyong Yang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The programmable self-assembly of molecular nanostructures plays a crucial role in the development of nanodevices for molecule recognition. A self-assembly, periodic ssDNA nanotemplate based on aptameric recognition of tumor marker, PDGF was in situ constructed on the silicon-based substrate. The long, periodic ssDNA nanotemplate was further elongated up to 454 nm through rolling circle amplification at room temperature. The process of self-growing DNA nanotemplate based on aptameric recognition was directly visualized through nanoprobing technology.

Original languageEnglish
Title of host publication2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009
Pages185-187
Number of pages3
DOIs
StatePublished - 1 Dec 2009
Event2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009 - Tainan, Taiwan
Duration: 18 Oct 200921 Oct 2009

Publication series

Name2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009

Conference

Conference2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009
CountryTaiwan
CityTainan
Period18/10/0921/10/09

Keywords

  • DNA
  • Nanodevice
  • Nanotemplate
  • Tumor marker

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