Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy

Veronika Lacková*, Natália Tomašovičová, Andrzej Olejniczak, Katarína Zakutanská, Jozefína Majorošová, Po Sheng Hu, Peter Kopčanský

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles’ adsorption on the amyloid fibrils’ surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.

Original languageEnglish
Article number166515
JournalJournal of Magnetism and Magnetic Materials
Volume502
DOIs
StatePublished - 15 May 2020

Keywords

  • Amyloid fibrils
  • Atomic force microscopy
  • Magnetic nanoparticles
  • Magnetization measurements

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