TY - JOUR
T1 - Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy
AU - Lacková, Veronika
AU - Tomašovičová, Natália
AU - Olejniczak, Andrzej
AU - Zakutanská, Katarína
AU - Majorošová, Jozefína
AU - Hu, Po Sheng
AU - Kopčanský, Peter
PY - 2020/5/15
Y1 - 2020/5/15
N2 - The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles’ adsorption on the amyloid fibrils’ surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.
AB - The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles’ adsorption on the amyloid fibrils’ surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.
KW - Amyloid fibrils
KW - Atomic force microscopy
KW - Magnetic nanoparticles
KW - Magnetization measurements
UR - http://www.scopus.com/inward/record.url?scp=85079002339&partnerID=8YFLogxK
U2 - 10.1016/j.jmmm.2020.166515
DO - 10.1016/j.jmmm.2020.166515
M3 - Article
AN - SCOPUS:85079002339
VL - 502
JO - Journal of Magnetism and Magnetic Materials
JF - Journal of Magnetism and Magnetic Materials
SN - 0304-8853
M1 - 166515
ER -