Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy

Veronika Lacková; Natália Tomašovičová; Andrzej Olejniczak; Katarína Zakutanská; Jozefína Majorošová; Po Sheng Hu; Peter Kopčanský

doi:10.1016/j.jmmm.2020.166515

Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy

Veronika Lacková^*, Natália Tomašovičová, Andrzej Olejniczak, Katarína Zakutanská, Jozefína Majorošová, Po Sheng Hu, Peter Kopčanský

^*Corresponding author for this work

Institute of Photonic System

Research output: Contribution to journal › Article › peer-review

Abstract

The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles’ adsorption on the amyloid fibrils’ surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.

Original language	English
Article number	166515
Journal	Journal of Magnetism and Magnetic Materials
Volume	502
DOIs	https://doi.org/10.1016/j.jmmm.2020.166515
State	Published - 15 May 2020

Keywords

Amyloid fibrils
Atomic force microscopy
Magnetic nanoparticles
Magnetization measurements

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@article{72f18fcbbea948029d0e077843843621,

title = "Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy",

abstract = "The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles{\textquoteright} adsorption on the amyloid fibrils{\textquoteright} surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.",

keywords = "Amyloid fibrils, Atomic force microscopy, Magnetic nanoparticles, Magnetization measurements",

author = "Veronika Lackov{\'a} and Nat{\'a}lia Toma{\v s}ovi{\v c}ov{\'a} and Andrzej Olejniczak and Katar{\'i}na Zakutansk{\'a} and Jozef{\'i}na Majoro{\v s}ov{\'a} and Hu, {Po Sheng} and Peter Kop{\v c}ansk{\'y}",

year = "2020",

month = may,

day = "15",

doi = "10.1016/j.jmmm.2020.166515",

language = "English",

volume = "502",

journal = "Journal of Magnetism and Magnetic Materials",

issn = "0304-8853",

publisher = "Elsevier",

}

Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy. / Lacková, Veronika; Tomašovičová, Natália; Olejniczak, Andrzej; Zakutanská, Katarína; Majorošová, Jozefína; Hu, Po Sheng; Kopčanský, Peter.

In: Journal of Magnetism and Magnetic Materials, Vol. 502, 166515, 15.05.2020.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Bio-inorganic nanocomposites of lysozyme amyloid fibrils and magnetic nanoparticles of different shape anisotropy

AU - Lacková, Veronika

AU - Tomašovičová, Natália

AU - Olejniczak, Andrzej

AU - Zakutanská, Katarína

AU - Majorošová, Jozefína

AU - Hu, Po Sheng

AU - Kopčanský, Peter

PY - 2020/5/15

Y1 - 2020/5/15

N2 - The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles’ adsorption on the amyloid fibrils’ surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.

AB - The present study describes the interaction of an assorted shape of magnetic nanoparticles with lysozyme amyloid fibrils by atomic force microscopy and magnetization measurements. Mixture stability was verified by settling behaviour of NPs dispersions. A fibril solution doped with spherically shaped magnetic nanoparticles reveals the effect of particles’ adsorption on the amyloid fibrils’ surface. However, when spindle-like magnetic nanoparticles were doped, it led to zero interaction activity, which confesses subtle difference in fibrillary interaction with spherical particle that can be explained by diverse size of nanoparticles. Moreover, spherical MNPs showed excellent stability in sLAF, the spindle MNPs were unstable and exhibited limited dispersion.

KW - Amyloid fibrils

KW - Atomic force microscopy

KW - Magnetic nanoparticles

KW - Magnetization measurements

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DO - 10.1016/j.jmmm.2020.166515

M3 - Article

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VL - 502

JO - Journal of Magnetism and Magnetic Materials

JF - Journal of Magnetism and Magnetic Materials

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