Atypical temporal activation pattern and central-right brain compensation during semantic judgment task in children with early left brain damage

Yi Tzu Chang, Shih che Lin, Ling fu Meng*, Yang Teng Fan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In this study we investigated the event-related potentials (ERPs) during the semantic judgment task (deciding if the two Chinese characters were semantically related or unrelated) to identify the timing of neural activation in children with early left brain damage (ELBD). The results demonstrated that compared with the controls, children with ELBD had (1) competitive accuracy and reaction time in the semantic judgment task, (2) weak operation of the N400, (3) stronger, earlier and later compensational positivities (referred to the enhanced P200, P250, and P600 amplitudes) in the central and right region of the brain to successfully engage in semantic judgment. Our preliminary findings indicate that temporally postlesional reorganization is in accordance with the proposed right-hemispheric organization of speech after early left-sided brain lesion. During semantic processing, the orthography has a greater effect on the children with ELBD, and a later semantic reanalysis (P600) is required due to the less efficient N400 at the former stage for semantic integration.

Original languageEnglish
Pages (from-to)37-43
Number of pages7
JournalBrain and Language
Volume177-178
DOIs
StatePublished - Feb 2018

Keywords

  • Brain plasticity
  • Cerebral palsy
  • Chinese character and word
  • Temporal brain potentials

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