Anti-NMDA receptor encephalitis and vaccination

Hsiuying Wang*

*Corresponding author for this work

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Anti-N-methyl-D-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune neurological disorder. The cause of this disease is often unknown, and previous studies revealed that it might be caused by a virus, vaccine or tumor. It occurs more often in females than in males. Several cases were reported to be related to vaccination such as the H1N1 vaccine and tetanus/diphtheria/pertussis and polio vaccines. In this study, we reported an anti-NMDA receptor encephalitis case that may be caused by Japanese encephalitis vaccination. To investigate the association between anti-NMDA receptor encephalitis and vaccination, we analyzed the phylogenetic relationship of the microRNAs, which significantly regulate these vaccine viruses or bacteria, and the phylogenetic relationship of these viruses and bacteria. This reveals that anti-NMDA receptor encephalitis may be caused by Japanese encephalitis vaccination, as well as H1N1 vaccination or tetanus/diphtheria/pertussis and polio vaccinations, from the phylogenetic viewpoint.

Original languageEnglish
Article number193
JournalInternational journal of molecular sciences
Volume18
Issue number1
DOIs
StatePublished - 18 Jan 2017

Keywords

  • Anti-NMDA receptor encephalitis
  • Japanese encephalitis
  • MicroRNA
  • Vaccination

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