Ammonium chiral borate salt catalyzed asymmetric Friedel-Crafts alkylation of indoles with α,β-disubstituted enals

Mitsuhiro Ueda*, Yoshitaka Yagyu, Ilhyong Ryu

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

In the presence of a catalytic amount of ammonium chiral borate salt, asymmetric Friedel-Crafts alkylation of indoles with α,β-disubstituted enals proceeded to give the corresponding 1,4-addition products with moderate enantioselectivities.

Original languageEnglish
Pages (from-to)1070-1077
Number of pages8
JournalTetrahedron Asymmetry
Volume28
Issue number8
DOIs
StatePublished - 15 Aug 2017

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