Air pollution is associated with poor cognitive function in taiwanese adults

Meng Chieh Chen, Chen Feng Wang, Bo Cheng Lai, Sun Wung Hsieh, Szu Chia Chen*, Chih Hsing Hung, Chao Hung Kuo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The issue of air pollution is gaining increasing attention worldwide, and mounting evidence has shown an association between air pollution and cognitive decline. The aim of this study was to investigate the relationships between air pollutants and cognitive impairment using the Mini-Mental State Exam (MMSE) and its sub-domains. In this study, we used data from the Taiwan Biobank combined with detailed daily data on air pollution. Cognitive function was assessed using the MMSE and its five subgroups of cognitive functioning. After multivariable linear regression analysis, a high level of particulate matter with an aerodynamic diameter of ≤2.5 µm (PM2.5), low ozone (O3), high carbon monoxide (CO), high sulfur dioxide (SO2), high nitric oxide (NO), high nitrogen dioxide (NO2), and high nitrogen oxide (NOx) were significantly associated with low total MMSE scores. Further, high SO2 and low O3 were significantly associated with low MMSE G1 scores. Low O3, high CO, high SO2, high NO2, and high NOx were significantly associated with low MMSE G4 scores, and high PM2.5, high particulate matter with an aerodynamic diameter of ≤10 µm (PM10), high SO2, high NO2, and high NOx were significantly associated with low MMSE G5 scores. Our results showed that exposure to different air pollutants may lead to general cognitive decline and impairment of specific domains of cognitive functioning, and O3 may be a protective factor. These findings may be helpful in the development of policies regarding the regulation of air pollution.

Original languageEnglish
Article number316
Pages (from-to)1-12
Number of pages12
JournalInternational journal of environmental research and public health
Volume18
Issue number1
DOIs
StatePublished - 1 Jan 2021

Keywords

  • Air pollutants
  • Cognitive decline
  • Mini-mental state exam
  • Sub-domains

Fingerprint Dive into the research topics of 'Air pollution is associated with poor cognitive function in taiwanese adults'. Together they form a unique fingerprint.

Cite this