Advanced plasmonic biosensing devices and automation systems for disease diagnostic and drug screening applications

Nan Fu Chiu, Tzuu Shaang Wey, Chun Yu, Tzu-Chien Hsiao, Chii Wann Lin*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Bio-plasmonics is proposed for the research and development of novel devices, which use biomolecules as a part of the plasmon oscillation system to actively interact with nano/micro structure. We have reported a novel design of Surface Plasmon Resonance (SPR) device and system, which uses alternative dielectric layers to enhance the SPR signal quality and modulate its resonant position. The use of biomolecular thin film, such as DNAs or Proteins, in this design can result in resonant condition of wavelength changes and thus can be detected by using nano-grating in the scattering mode with ehanced feature due to resonance. According to our calculation, it can provide ultra sensitivity system (dLx/dn) of 10 8 for biosensor applications. The fundamental SPR principle and extended application of these fundamental principles and novel devices, including screening and diagnosis, will be discussed SPR-system to control is the ability. SPR-system has the ability to detect, in near real-time, the concentration of a target analyte and biosensing is viewed as a key application domain for this new technology.

Original languageEnglish
Title of host publicationProceedings - 8th International Conference on Intelligent Systems Design and Applications, ISDA 2008
Pages171-176
Number of pages6
DOIs
StatePublished - 1 Dec 2008
Event8th International Conference on Intelligent Systems Design and Applications, ISDA 2008 - Kaohsiung, Taiwan
Duration: 26 Nov 200828 Nov 2008

Publication series

NameProceedings - 8th International Conference on Intelligent Systems Design and Applications, ISDA 2008
Volume1

Conference

Conference8th International Conference on Intelligent Systems Design and Applications, ISDA 2008
CountryTaiwan
CityKaohsiung
Period26/11/0828/11/08

Keywords

  • Bio-plasmonics
  • Biosensor
  • DNAs
  • Proteins
  • Surface plasmon polaritons (SPPs)

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    Chiu, N. F., Wey, T. S., Yu, C., Hsiao, T-C., & Lin, C. W. (2008). Advanced plasmonic biosensing devices and automation systems for disease diagnostic and drug screening applications. In Proceedings - 8th International Conference on Intelligent Systems Design and Applications, ISDA 2008 (pp. 171-176). [4696198] (Proceedings - 8th International Conference on Intelligent Systems Design and Applications, ISDA 2008; Vol. 1). https://doi.org/10.1109/ISDA.2008.39