Addition of allyl bromide to phenylacetylene catalyzed by palladium on alumina and its application to a continuous flow synthesis

Takahide Fukuyama, Takashi Kippo, Ilhyong Ryu*, Takahiro Sagae

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The reaction of allyl bromide with phenylacetylene catalyzed by Pd/Al 2O3 pellets and Pd/C powder was investigated. Bromoallylation of phenylacetylene took place to give a regioisomeric mixture of 1-bromo-substituted 1, 4-dienes. The bromoallylation of phenylacetylene was successfully applied to a continuous flow synthesis using a stainless steel made column packed with Pd/Al2O3 pellets.

Original languageEnglish
Pages (from-to)1053-1057
Number of pages5
JournalResearch on Chemical Intermediates
Volume35
Issue number8-9
DOIs
StatePublished - 1 Nov 2009

Keywords

  • Bromoallylation
  • Continuous flow synthesis
  • Palladium on alumina
  • Palladium on carbon

Fingerprint Dive into the research topics of 'Addition of allyl bromide to phenylacetylene catalyzed by palladium on alumina and its application to a continuous flow synthesis'. Together they form a unique fingerprint.

  • Cite this