A rapid and portable sensor based on protein-modified gold nanoparticle probes and lateral flow assay for naked eye detection of mercury ion

Cheng Han Chao, Chung Shu Wu, Chung Chih Huang, Jie Chian Liang, Hsiao Ting Wang, Pin Ting Tang, Lih Yuan Lin*, Fu-Hsiang Ko

*Corresponding author for this work

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Contamination of the environment with heavy metal ions has been an important worldwide concern for decades. Among them, mercury ion (Hg 2+) is one of the heavy metal ion maintained in the detection because of its toxicity. In this study, we have designed the gold nanoparticle (AuNP) probes of carboxylic modified protein and employed the lateral flow assay to detect the Hg 2+ without complicated instrumentations and technical expertise. The captured AuNP probes on the test zone and control zone of the sensor produced the characteristic red bands, enabling visual discrimination of Hg 2+ concentrations. The demand of Hg 2+ analysis in environmental applications requires parallel analytical strategies; such a method with simplicity and rapidity has enormous potential for the application of Hg 2+ monitoring in environment, water, and food samples.

Original languageEnglish
Pages (from-to)294-296
Number of pages3
JournalMicroelectronic Engineering
Volume97
DOIs
StatePublished - 1 Sep 2012

Keywords

  • Gold nanoparticle
  • Lateral flow assay
  • Mercury ion
  • Sensor

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