A Novel Handheld Diffuse Optical Spectroscopy System Implementation Based on High-Accuracy Multidimensional Imaging Reconstruction Model for Human Breast Healthcare Applications

Jia Jiun Guo, Wen Jun Wu, Wai Chi Fang*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Diffuse Optical Tomography (DOT) is a relatively novel, nonionizing and noninvasive technique for breast tumor imaging. Due to the diffusive nature of light propagation, the inverse problem is highly ill-posed. In this study, we propose the modified Beer-Lambert's law that reduces the number of unknown values to reduce the ill-posedness issue. An integrated mobile DOT system is proposed. The system comprises a front-end circuit and an integrated digital signal processor. The sources and the detectors are distributed hexagonal geometry for increasing the spatial resolution. The processor included the front-end controller, the iteration algorithm engine and wireless communication controller were implemented on FPGA. The functionalities of the proposed system were validated using a breast phantom. Extensive experimental results illustrated to show the performance of the proposed system. The depth of the tumor detected by the system is 20mm.

Original languageEnglish
Title of host publicationBioCAS 2019 - Biomedical Circuits and Systems Conference, Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781509006175
DOIs
StatePublished - Oct 2019
Event2019 IEEE Biomedical Circuits and Systems Conference, BioCAS 2019 - Nara, Japan
Duration: 17 Oct 201919 Oct 2019

Publication series

NameBioCAS 2019 - Biomedical Circuits and Systems Conference, Proceedings

Conference

Conference2019 IEEE Biomedical Circuits and Systems Conference, BioCAS 2019
CountryJapan
CityNara
Period17/10/1919/10/19

Keywords

  • Diffuse optical tomography
  • iteration method
  • portable system
  • reconstruction algorithm

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