A miniature CMOS optoelectronic biosensor for screening skin-whitening agents

Yu Wei Chang*, Yen Pei Lu, Ming Yu Lin, Yang Tung Huang, Yuh-Shyong Yang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A miniature CMOS optoelectronic biosensor is proposed for screening whitening agents. Based on the principle of absorption photometry, this biosensor is mainly composed of a green LED, a CMOS phototransistor, and a slide for performing the biochemical reactions. The requirement of the sample volume is only 10 μl, much less than those in commercial instruments. Melanin assay and MTT assay were performed to evaluate the whitening mechanisms. Experimental results demonstrated that the density of 5x104 cells/ml can be successfully detected for both assays. This portable biosensor has great potential toward personalized diagnostic kits for further applications.

Original languageEnglish
Title of host publicationNEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference
DOIs
StatePublished - 21 Sep 2009
EventIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009 - Boston, MA, United States
Duration: 3 Apr 20095 Apr 2009

Publication series

NameBioengineering, Proceedings of the Northeast Conference
ISSN (Print)1071-121X

Conference

ConferenceIEEE 35th Annual Northeast Bioengineering Conference, NEBEC 2009
CountryUnited States
CityBoston, MA
Period3/04/095/04/09

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  • Cite this

    Chang, Y. W., Lu, Y. P., Lin, M. Y., Huang, Y. T., & Yang, Y-S. (2009). A miniature CMOS optoelectronic biosensor for screening skin-whitening agents. In NEBEC 2009 - Proceedings of the IEEE 35th Annual Northeast Bioengineering Conference [4967712] (Bioengineering, Proceedings of the Northeast Conference). https://doi.org/10.1109/NEBC.2009.4967712