A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells

Jiun Ting Yeh, Parthiban Venkatesan, Shu-Pao Wu*

*Corresponding author for this work

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

A fluorescent probe (FS) based on a fluoride-specific desilylation reaction has been developed for a highly selective and sensitive detection of F-. In the presence of F-, the probe FS provided significant green fluorescence enhancement, while other anions produced only minor changes in fluorescence intensity. The probe FS has a limit of detection of 1.45 μM, which is reasonable for the detection of micromolar concentrations of F- ions. The maximum fluorescence enhancement induced by F- in the probe was observed over the pH range 7-10. Moreover, fluorescence microscopy imaging using mouse leukaemic monocyte macrophage showed that the probe FS could be an efficient fluorescent probe for F- ions in living cells. This journal is

Original languageEnglish
Pages (from-to)6198-6204
Number of pages7
JournalNew Journal of Chemistry
Volume38
Issue number12
DOIs
StatePublished - 1 Dec 2014

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