A half-ring GMR sensor for detection of magnetic beads immobilized on a circular micro-trap

C. P. Gooneratne*, C. Liang, Artur Useinov, J. Kosel, I. Giouroudi

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Utilizing magnetic principles in biological immunoassays is an attractive option given its ability to remotely and non-invasively manipulate and detect cells tagged with micro/nano size superparamagnetic type beads and due to the fact that even the most complex biological immunoassays will have very little magnetic effect. The presence of magnetic beads can be detected by a magnetic sensor which quantifies the amount of target cells present in the immunoassay. In order to increase the detection rate a circular conducting micro-trap is employed to attract, trap and transport the magnetic beads to the sensing area. In this research we propose a half-ring spin valve type giant magnetoresistance (GMR) sensor for the measurement of stray fields produced by 2 μm magnetic beads which are around the circular micro-trap. A couple of half-ring GMR sensors can be used to cover the entire circular border width, in order to detect the majority of the immobilized magnetic beads. Analytical and numerical analysis leading towards the fabrication of the half-ring GMR sensor are presented. DC characterization of the fabricated sensor showed a magnetoresistance of 5.9 %. Experimental results showed that the half-ring GMR sensor detected the presence of 2 μm magnetic beads. Hence, half-ring GMR sensors integrated with a circular micro-trap have great potential to be used as an effective disease diagnostic device.

Original languageEnglish
Title of host publication2011 5th International Conference on Sensing Technology, ICST 2011
Pages106-111
Number of pages6
DOIs
StatePublished - 1 Dec 2011
Event2011 5th International Conference on Sensing Technology, ICST 2011 - Palmerston North, New Zealand
Duration: 28 Nov 20111 Dec 2011

Publication series

NameProceedings of the International Conference on Sensing Technology, ICST
ISSN (Print)2156-8065
ISSN (Electronic)2156-8073

Conference

Conference2011 5th International Conference on Sensing Technology, ICST 2011
CountryNew Zealand
CityPalmerston North
Period28/11/111/12/11

Keywords

  • GMR sensor
  • immunoassay
  • magnetic beads
  • magnetic force
  • microtrap

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    Gooneratne, C. P., Liang, C., Useinov, A., Kosel, J., & Giouroudi, I. (2011). A half-ring GMR sensor for detection of magnetic beads immobilized on a circular micro-trap. In 2011 5th International Conference on Sensing Technology, ICST 2011 (pp. 106-111). [6136942] (Proceedings of the International Conference on Sensing Technology, ICST). https://doi.org/10.1109/ICSensT.2011.6136942