Abstract
The PdCl2(PPh3)2-catalyzed Sonogashira coupling reaction, in good to high yields, was performed in an ionic liquid ([BMIm][PF6]) in the absence of a copper salt. The use of an ionic liquid allows for the facile separation and recycling of the catalyst. The application of the above reaction in a microflow system in conjunction with an IMM micromixer was also successful.
Original language | English |
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Pages (from-to) | 1691-1694 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 4 |
Issue number | 10 |
DOIs | |
State | Published - 16 May 2002 |