A CMOS 256-Pixel Self-Photovoltaics-Powered Subretinal Prosthetic Chip with Wide Image Dynamic Range and Shared Electrodes and Its in Vitro Experimental Results on Rd1 Mice

Chung-Yu Wu, Chi Kuan Tzeng, Shih Yun Huang, Fang Liang Chu, Chuan Chin Chiao, Yueh Chun Tsai, Jun Ohta, Toshihiko Noda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A self-photovoltaics-powered CMOS 256-pixel implantable chip with wide image dynamic range and shared electrodes is proposed and fabricated for subretinal prostheses. The infra-red (IR) light is incident only on photovoltaic cells of the chip whereas the visible light is mainly incident on pixels. The proposed adaptive background cancellation circuit (ABCC) is adopted to increase the image dynamic range so that the subretinal chip can adapt for different surrounding illuminances. Moreover, the bi-directional sharing electrodes (BDSEs) is used to increase electrode size under the same chip area and boost the stimulation charges to 11.4 nC. The functions of the chip have been successfully validated with both electrical measurement and in vitro patch clamp experiments with the retinas of Rd1 mice.

Original languageEnglish
Title of host publication2019 IEEE 62nd International Midwest Symposium on Circuits and Systems, MWSCAS 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages29-32
Number of pages4
ISBN (Electronic)9781728127880
DOIs
StatePublished - Aug 2019
Event62nd IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2019 - Dallas, United States
Duration: 4 Aug 20197 Aug 2019

Publication series

NameMidwest Symposium on Circuits and Systems
Volume2019-August
ISSN (Print)1548-3746

Conference

Conference62nd IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2019
CountryUnited States
CityDallas
Period4/08/197/08/19

Keywords

  • CMOS image sensor
  • implantable chip
  • subretinal prostheses

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  • Cite this

    Wu, C-Y., Tzeng, C. K., Huang, S. Y., Chu, F. L., Chiao, C. C., Tsai, Y. C., Ohta, J., & Noda, T. (2019). A CMOS 256-Pixel Self-Photovoltaics-Powered Subretinal Prosthetic Chip with Wide Image Dynamic Range and Shared Electrodes and Its in Vitro Experimental Results on Rd1 Mice. In 2019 IEEE 62nd International Midwest Symposium on Circuits and Systems, MWSCAS 2019 (pp. 29-32). [8885223] (Midwest Symposium on Circuits and Systems; Vol. 2019-August). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MWSCAS.2019.8885223