The Avalanche Photodiodes (APDs) are widely used in a variety of optical application requiring high sensitivity, such as long-distance optical communication and optical distance measurement, because the APDs can detect the low level light. APDs accompanied with the Transimpedance Amplifier (TIA) are utilized on the receiver side in the communication system. The trend of integrating the active optical components faces the challenge of integrating different voltage levels. In general, the operation voltage of TIA is usually 1.8 V or 3.3 V. However, the APD requires a high reverse-biasing voltage of 40 V - 80 V. Therefore, a high conversation-ratio boost converter must be included to provide the high voltage to bias the APD. Besides, output voltage ripple must be minimized to decrease the influence on communication signals. Experimental results show the 80 V output voltage boosted from the input voltage of 2.5 V. The output voltage ripple is 2 mV under the condition of 1 mA load current.