A 16-channel CMOS chopper-stabilized analog front-end acquisition circuits for ECoG detection

Cheng Hsiang Cheng, Zhi Xin Chen, Chung-Yu Wu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

In this paper, a 16-channel analog front-end (AFE) ECoG-signal acquisition circuit for closed-loop seizure control system is presented. It is composed of 16 auto-reset chopper-stabilized capacitive-coupled instrumentation amplifiers (AR-CSCCIA) with band-pass filters, 16 programmable transconductance-gain amplifiers, a multiplexer, a transimpedance amplifier, and a 10-bit SAR ADC. The low input-referred noise is achieved by using chopper modulation technique in AR-CSCCIA. To reduce the undesired effects of chopper modulation, an improved offset reduction loop (ORL) is proposed to reduce output offset generated by input chopper mismatches. The digital ripple reduction loop (RRL) is also used to reduce chopper ripple. Moreover, to prevent from overstress in MOS devices caused by high stimulation voltage, an input protection circuit with high-voltage-tolerant switches is proposed to make the AFE amplifiers sharing the same electrode with high voltage stimulators. The fabricated AFE acquisition circuit has 49.1/59.1/67.9 dB programmable gain and 2.09uVrms input referred noise in a bandwidth 0.5-100 Hz. The measured power consumption of AFE is 3.26 uW per channel and the noise efficiency factor (NEF) is 3.78.

Original languageEnglish
Title of host publicationIEEE International Symposium on Circuits and Systems
Subtitle of host publicationFrom Dreams to Innovation, ISCAS 2017 - Conference Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467368520
DOIs
StatePublished - 25 Sep 2017
Event50th IEEE International Symposium on Circuits and Systems, ISCAS 2017 - Baltimore, United States
Duration: 28 May 201731 May 2017

Publication series

NameProceedings - IEEE International Symposium on Circuits and Systems
ISSN (Print)0271-4310

Conference

Conference50th IEEE International Symposium on Circuits and Systems, ISCAS 2017
CountryUnited States
CityBaltimore
Period28/05/1731/05/17

Keywords

  • chopper-stabilized
  • low noise
  • low power
  • neural-signal amplifier
  • offset reduction loop
  • ripple reduction loop

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    Cheng, C. H., Chen, Z. X., & Wu, C-Y. (2017). A 16-channel CMOS chopper-stabilized analog front-end acquisition circuits for ECoG detection. In IEEE International Symposium on Circuits and Systems: From Dreams to Innovation, ISCAS 2017 - Conference Proceedings [8050954] (Proceedings - IEEE International Symposium on Circuits and Systems). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISCAS.2017.8050954