3D imaging devices, such as stereo and time-of-flight (ToF) cameras, measure distances to the observed points and generate a depth image where each pixel represents a distance to the corresponding location. The depth image can be converted into a 3D point cloud using simple linear operations. This spatial information provides detailed understanding of the environment and is currently employed in a wide range of applications such as human motion capture . However, its distinct characteristics from conventional color images necessitate different approaches to efficiently extract useful information. This paper describes a low-power vision processor for processing such 3D image data. The processor achieves high energy-efficiency through a parallelized reconfigurable architecture and hardware-oriented algorithmic optimizations. The processor will be used as a part of a navigation device for the visually impaired (Fig. 24.1.1). This handheld or body-worn device is designed to detect safe areas and obstacles and provide feedback to a user. We employ a ToF camera as the main sensor in this system since it has a small form factor and requires relatively low computational complexity .