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Personal profile

Research Interests

Molecular Simulation, Statistical Mechanics, Protein Dynamics, Drug Discovery

Experience

2004/7~2006/8 Postdoctoral Researcher, Department of Chemistry, University of Utah

2006/9~2013/7 Assistant Professor, Department of Chemical and Biomolecular Engineering, University of California, Berkeley

2013/8~ present Professor, Institute of Bioinformatics and Systems Biology, National Chiao Tung University

Education/Academic qualification

PhD, Massachusetts Institute of Technology

External positions

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Projects

利用分子模擬和結構機械統計學習分析三端修復外切核酸酶1所具特有活性之分子機制(1/3)

Chu, J.

1/08/2031/07/21

Project: Government MinistryMinistry of Science and Technology

建立多層級模擬計算方法以解譯蛋白質動態與功能(3/3)

Chu, J.

1/08/1931/07/20

Project: Government MinistryMinistry of Science and Technology

建立多層級模擬計算方法以解譯蛋白質動態與功能(2/3)

Chu, J.

1/08/1831/07/19

Project: Government MinistryMinistry of Science and Technology

Development and Application of Multiscale Computational Methods to Decipher Protein Dynamics and Function

Chu, J.

1/08/1731/07/18

Project: Government MinistryMinistry of Science and Technology

Developing a Multiscale /Multiphysics Computational Framework for Predicative Modeling and Simulation of Protein Machines

Chu, J.

1/08/1631/07/17

Project: Government MinistryMinistry of Science and Technology

Research Output

Basal leakage in oscillation: Coupled transcriptional and translational control using feed-forward loops

Joanito, I., Yan, C. C. S., Chu, J-W., Wu, S. H. & Hsu, C. P., 1 Sep 2020, In : PLoS Computational Biology. 16, 9, p. e1007740

Research output: Contribution to journalArticle

Open Access
  • Structure-mechanics statistical learning unravels the linkage between local rigidity and global flexibility in nucleic acids

    Chen, Y. T., Yang, H. & Chu, J. W., 21 May 2020, In : Chemical Science. 11, 19, p. 4969-4979 11 p.

    Research output: Contribution to journalArticle

    Open Access
  • An incoherent feed-forward loop switches the Arabidopsis clock rapidly between two hysteretic states

    Joanito, I., Chu, J-W., Wu, S. H. & Hsu, C. P., 1 Dec 2018, In : Scientific reports. 8, 1, 13944.

    Research output: Contribution to journalArticle

    Open Access
  • 7 Scopus citations

    Compound Molecular Logic in Accessing the Active Site of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B

    Morrell, T. E., Rafalska-Metcalf, I. U., Yang, H. & Chu, J-W., 7 Nov 2018, In : Journal of the American Chemical Society. 140, 44, p. 14747-14752 6 p.

    Research output: Contribution to journalArticle

  • Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1

    Huang, K. W., Liu, T. C., Liang, R. Y., Chu, L. Y., Cheng, H. L., Chu, J-W. & Hsiao, Y-Y., 7 May 2018, In : PLoS Biology. 16, 5, e2005653.

    Research output: Contribution to journalArticle

    Open Access
  • 6 Scopus citations