Projects per year
Organization profile
organization profile
The NCTU Bioinformatics and Systems Biology Institute is the first Institute of Bioinformatics and is ranked among the best in Taiwan, as evidenced by the excellence of the faculty and students as well as the quality of interdisciplinary educational programs. The Major is designed for highly motivated students interested in interdisciplinary activities in life sciences, computer science, statistics, systems biology, and computational biology. Leading the Institute's research and teaching activities are 10 professors and 5 core facilities (e.g. over 300-cpu PC clusters and 40 MAC computers). The Institute has over 28 and 40 graduate students pursuing master and doctorate degrees, respectively.
The NCTU Institute of Bioinformatics and Systems Biology carries out research in structural bioinformatics, systems biology (e.g. gene networks and metabolic pathways), drug discovery, biological databases and algorithms, molecular evolution, computational chemistry, and functional genomics. Supporting by National Science Council and Ministry of Education, the Institute has installed the sole Structural Bioinformatics and Computer-aided Drug Design Core Facilities. On average, each faculty publishes 5 papers/year and the sum of impact factor is over 20/year; and the grant is over 3,000,000/year. These Principle Investigators have produced renowned computational packages and databases: GEMDOCK, for drug design; 3D-BLAST, for a super fast structure database search; miRNAMap, genomic maps of microRNAs in mammalian genomes; and CELLO, for sub-cellular localization prediction.
The Molecular Bioinformatics Center (MBC) was established in 2006 as a national resource for bioinformatics and computational systems biology in Taiwan. MBC performs research in computational biology, develops software tools and novel algorithms for analyzing biological data and creates public databases. The research areas cover protein structure prediction and classification, computational drug docking, protein thermostability prediction, data mining, RNA secondary structure prediction and large-scale genomic sequence alignment.
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Profiles
Projects
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從患者個體至單細胞之癌症聚焦網路應用於開發個人化生物標記及癌症治療(2/5)
1/09/20 → 31/08/21
Project: Government Ministry › Ministry of Science and Technology
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腦機介面系統於智慧控制下肢復健機提升神經回饋復健功效
1/08/20 → 31/07/21
Project: Government Ministry › Ministry of Science and Technology
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開發耳內式腦波感測與迷走神經刺激裝置於偏頭痛預測與治療
1/08/20 → 31/07/21
Project: Government Ministry › Ministry of Science and Technology
Research output
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APE1 distinguishes DNA substrates in exonucleolytic cleavage by induced space-filling
Liu, T. C., Lin, C. T., Chang, K. C., Guo, K. W., Wang, S., Chu, J. W. & Hsiao, Y. Y., Dec 2021, In: Nature Communications. 12, 1, 601.Research output: Contribution to journal › Article › peer-review
Open Access -
A pilot study on essential oil aroma stimulation for enhancing slow-wave EEG in sleeping brain
Ko, L. W., Su, C. H., Yang, M. H., Liu, S. Y. & Su, T. P., Dec 2021, In: Scientific reports. 11, 1, 1078.Research output: Contribution to journal › Article › peer-review
Open Access -
A TD-DFT molecular screening for fluorescence probe based on excited-state intramolecular proton transfer of 2’-hydroxychalcone derivatives
Chansen, W., Yu, J. S. K. & Kungwan, N., 1 Apr 2021, In: Journal of Photochemistry and Photobiology A: Chemistry. 410, 113165.Research output: Contribution to journal › Article › peer-review
Prizes
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13th Macronix Golden Silicon Awards Semiconductor Design and Application Competition, Second Runner-up in Application Category
Ko, Li-Wei (Recipient), 2013
Prize: Honorary award
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15th Macronix Golden Silicon Awards Semiconductor Design and Application Competition, Third Runner-up in Application Category
Ko, Li-Wei (Recipient), 2015
Prize: Honorary award
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Academic achievement award in the Institute of Bioinformatics and Systems Biology, National Chiao Tung University
Lin, Chun-Yu (Recipient), 2009
Prize: Honorary award
Activities
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IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING (Event)
Li-Wei Ko (Member of editorial board)
1 Jan 2018 → 31 Dec 2018Activity: Publication peer-review and editorial work › Editorial work
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PLoS One (Event)
Jinn-Moon Yang (Member of editorial board)
1 Jan 2017 → 31 Dec 2018Activity: Publication peer-review and editorial work › Editorial work
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Scientific Reports (Event)
Jinn-Moon Yang (Member of editorial board)
1 Jan 2017 → 22 Dec 2018Activity: Publication peer-review and editorial work › Editorial work